Sr Scientist - Analytical and Biological Mass Spectrometry (ABMS)

Company: Regeneron Pharmaceuticals, Inc.
Location: Tarrytown
Posted on: March 11, 2026

Job Description:

Regeneron Pharmaceutical's Analytical and Biological Mass Spectrometry Group (ABMS), located in Tarrytown, NY is seeking a highly motivated Sr. Scientist. In this role, you will work in an innovative mass spectrometry lab and develop LC-MS methods for characterizing biotherapeutic products to support all stages of drug development, from early-stage candidate selections to late-stage regulatory submissions. You will conduct and develop innovative technologies to support a diverse Regeneron's R&D pipeline. A Typical Day In This Role Looks Like: Lead and deliver on characterization activities to elucidate product quality attributes like post-translational modifications, sequence variants, charge variants, size variants, and host cell proteins. Provide technical support for cross-functional teams, including formulation development, upstream and downstream process development, manufacturing and help to tackle real-time development challenges in process development and manufacturing for OOS/OOT investigations. Proactively find opportunities to advance LC-MS analysis of biotherapeutics by developing technical innovations that will contribute to future developmental needs and/or efficiency gains. Perform sample preparation and LC-MS-based experiments independently based on SOPs and document experiments, results and findings in electronic laboratory notebook (ELN). Prepare and review regulatory submission documents like IND, comparability, and BLA reports, as well as manuscripts for publication in peer-reviewed journals. Serve as the team representative, provide analytical expertise to cross-functional teams, and present findings at internal and external meetings. This Role May Be For You If: You thrive in a fast-paced, collaborative environment and consistently deliver results with efficiency and ownership. You quickly learn new technologies, tackle complex problems, and have a passion for science. You are self-motivated and proactive, prioritizing effectively, and driving work forward with minimal supervision. To be considered for this role, you must have a BS (10 years), MS (7 years) or PhD degree (0-3 years) in Analytical Chemistry, Biochemistry, Pharmaceutical Sciences, or a closely related field. Extensive experience with advanced mass spectrometers (Orbitrap, Q-TOF, Triple Quadrupole, etc.), liquid chromatography, and data processing software (Proteome Discoverer, Skyline, Protein Metrics, etc.) is desired. Knowledge and experience with extended characterization of monoclonal antibodies by mass spectrometry to support cell line and upstream/downstream development is a plus. Experience with automated liquid-handling systems (e.g., Bravo, KingFisher) and with experimental design and data analysis (e.g., design of experiments, molecular modeling, graphing, and statistical analysis software such as JMP) is a plus. Does this sound like you? Apply now to take your first step towards living the Regeneron Way! We have an inclusive culture that provides comprehensive benefits, which vary by location. In the U.S., benefits may include health and wellness programs (including medical, dental, vision, life, and disability insurance), fitness centers, 401(k) company match, family support benefits, equity awards, annual bonuses, paid time off, and paid leaves (e.g., military and parental leave) for eligible employees at all levels! For additional information about Regeneron benefits in the US, please visit https://careers.regeneron.com/en/working-at-regeneron/total-rewards/. For other countries specific benefits, please speak to your recruiter. Please be advised that at Regeneron, we believe we are most successful and work best when we are together. For that reason, many of Regenerons roles are required to be performed on-site. Please speak with your recruiter and hiring manager for more information about Regenerons on-site policy and expectations for your role and your location. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, nationality, national or ethnic origin, civil status, age, citizenship status, membership of the Traveler community, sexual orientation, disability, genetic information, familial status, marital or registered civil partnership status, pregnancy or parental status, gender identity, gender reassignment, military or veteran status, or any other protected characteristic in accordance with applicable laws and regulations. The Company will also provide reasonable accommodation to the known disabilities or chronic illnesses of an otherwise qualified applicant for employment, unless the accommodation would impose undue hardship on the operation of the Company's business. For roles in which the hired candidate will be working in the U.S., the salary ranges provided are shown in accordance with U.S. law and apply to U.S.-based positions. For roles which will be based in Japan and/or Canada, the salary ranges are shown in accordance with the applicable local law and currency. If you are outside the U.S, Japan or Canada, please speak with your recruiter about salaries and benefits in your location. Please note that certain background checks will form part of the recruitment process. Background checks will be conducted in accordance with the law of the country where the position is based, including the type of background checks conducted. The purpose of carrying out such checks is for Regeneron to verify certain information regarding a candidate prior to the commencement of employment such as identity, right to work, educational qualifications etc. Salary Range (annually) $109,900.00 - $179,300.00

Keywords: Regeneron Pharmaceuticals, Inc., Greenwich , Sr Scientist - Analytical and Biological Mass Spectrometry (ABMS), Science, Research & Development , Tarrytown, Connecticut